Endocrine Abstracts

Background: An “empty sella” is characterised by a sella turcica filled with cerebrospinal fluid. It is called primary when the empty sella is not linked to any pathological process of the pituitary itself. The prevalence of empty sella has been reported in up to 38% of imaging studies. Some patients may present with endocrine, neurological and ophthalmological symptoms due to the aberrant anatomy of the sellar region. The aim of this study was to analyse clinical pr...

Two nationwide surveys on acromegaly (AcroBel-1 and 2) have been performed in Belgium at an interval of five years, including centralized GH and IGF1 measurements in most patients. A normal IGF1 for age was observed in 56% of 311 vs 74% of 365 treated patients, in 2004 and 2009 respectively.Factors responsible for this improvement were investigated. A selection bias was unlikely as the follow-up rate was higher in patients with active (83%) or medically ...

Introduction: Autoimmune disease is a rare event occurring after remission of Cushing’s syndrome. We report on the appearance of new onset vitiligo in a patient treated for Cushing disease due to a an invasive pituitary adenoma, after bilateral adrenalectomy.Case report: A 64-year-old man presented to our endocrinology clinic with progressive lumbar pain that had developed two months earlier. He had undergone bilateral adrenalectomy for Cushing&#146...

To evaluate the epidemiology and global quality of care of acromegaly in Belgium, all endocrinologists treating patients with acromegaly were invited to participate in a nationwide survey extending from 15-6-2003 till 30-9-2004, aiming to include all patients (including deaths) that were in follow up or newly diagnosed after 1-1-2000. The project was ethically approved and written informed consent obtained. Retrospective data on demographics, pathology, complications and treat...